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Covid-19 Damages the Heart resulting in Inflammation!

Written by Mary Pooja

Since the coronavirus epidemic, the confirmed cases in India is skyrocketing which resulted in capturing the “Third position” for the worst affected Nations by Covid-19. Aside from the fact that the recovery rate have paced up ahead bringing to an overall 1.07M cases.  A recent-studies have proved to show that Covid-19 can damage added to the lungs.

According to the JAMA Cardiology, have published in one of the journals saying, “there is a prolong impact on heart health to those who have recovered from illness and may have caused cardiac infection.” Let’s get into a detailed study from where it all starts…

The Coronavirus may Directly Injure the Heart

The virus can also directly infect cells within the cardiovascular system. The coronavirus infects the body via a receptor called the angiotensin converting enzyme 2, or ACE2.  ACE2 receptors are prevalent within the lungs, hence the respiratory symptoms, but they’re within the heart and blood vessels, too.

According to Dr. Jack Wolfson, a board certified cardiologist and a fellow of the American College of Cardiology, the coronavirus appears to enter and infect the heart cells though these ACE2 receptors. “Once inside the heart cell, damage to the cellular machinery directly from the virus and therefore the human immune cell response results in cell dysfunction and cellular death,” Wolfson said.

Many Patients have Underlying Heart Issues

Many patients who develop severe COVID-19 complications have already got underlying heart issues. One study watching over 72,000 patients with COVID-19 found that about 22 percent of patients who died had cardiovascular comorbidities.

“A person with pre-existing vessel ” arteria coronaria disease is more likely to experience cardiac complications since they have already got compromised blood flow to their heart and diminished blood vessel function,” Wolfson said.

To know how it affects the cardiovascular system an MRI Scan was done to a patient – who got recovered from Covid-19.

Case Study:

High-sensitivity troponin T level on the day of cardiac magnetic resonance imaging was 17.8 pg/mL. The patient recovered at home from COVID-19 illness with minimal symptoms, which included loss of smell and taste and only mildly increased temperature lasting 2 days. There were no known previous conditions or regular medication use. Histology revealed intracellular edema as enlarged cardiomyocytes with no evidence of interstitial or replacement fibrosis. A and B, Immunohistochemical staining revealed acute lymphocytic infiltration (lymphocyte function–associated antigen 1 and activated lymphocyte T antigen CD45R0), as well as activated intercellular adhesion molecule 1. C and D, Cardiac magnetic resonance imaging revealed enlarged volumes in myocardial mapping acquisitions, including significantly raised native T1 and native T2. E and F, Pericardial effusion and enhancement (yellow arrowheads) and epicardial and intramyocardial enhancement (white arrowheads) were seen on late gadolinium enhancement (LGE) acquisition. Courtesy: JAMA Cardiology

Experimental Medications Also can Increase a Person’s Risk

“Anti-inflammatories and antivirals impact the system and therefore the cardiac muscle in many various ways, a number of which could lead on to lethal heart rhythms within the short term or worsen heart recovery within the future ,” Wolfson said.

Additionally, glucocorticoids, which are accustomed to reduce inflammation, also are known to boost blood glucose levels, which may trigger complications in people that have coronary artery disease. and therefore the antiviral drugs being experimentally used on patients with COVID-19 can potentially alter the channels within the heart cells and cause arrhythmias and wearing of the guts muscle.

The Bottom Line

Even though COVID-19 is considered an illness of the lungs, many patients who contract the new coronavirus experience cardiac issues. Recent research suggests there are a couple of mechanisms on why COVID-19 damages the heart: the widespread inflammation the infection causes, the likelihood that the virus directly infects and injures the cardiovascular system, and therefore the overall stress the infection puts on preexisting heart conditions.

Still, more research is required to verify exactly how the coronavirus affects heart function, and which patients with COVID-19 are most in danger for running into heart troubles.

To Read More Click On the Link Below:

Sources

https://www.healthline.com/health-news/how-covid-19-triggers-heart-conditions#The-coronavirus-may-directly-injure-the-heart

https://www.msn.com/en-us/health/medical/covid-19-and-the-heart-two-new-studies-offer-insights/ar-BB17imFH?li=BBnba9O

https://www.diagnosticimaging.com/view/cardiac-mri-reveals-post-recovery-heart-damage-in-78-percent-of-covid-19-patients

About the author

Mary Pooja